Redox regulation of the afferent arteriole and tubuloglomerular feedback.

@article{Wilcox2003RedoxRO,
  title={Redox regulation of the afferent arteriole and tubuloglomerular feedback.},
  author={Christopher Stuart Wilcox},
  journal={Acta physiologica Scandinavica},
  year={2003},
  volume={179 3},
  pages={217-23}
}
Oxidative stress implies an increased production of reactive oxygen species (ROS) or a decreased capacity to metabolize them. Superoxide anion (O) can bioinactivate nitric oxide (NO). Therefore, many effects of ROS are manifest as NO deficiency. The afferent arteriole and macula densa cell both contain a full complement of components of nicotine adenine dinucleotide phosphate (NADPH) oxidase that generates O. Nitric oxide synthase (NOS) type 1 or neuronal NOS (nNOS) is expressed in the macula… CONTINUE READING