Redox regulation of resveratrol-mediated switching of death signal into survival signal.

@article{Das2008RedoxRO,
  title={Redox regulation of resveratrol-mediated switching of death signal into survival signal.},
  author={Samarjit Das and Nadeem Akbar Khan and Subhendu Mukherjee and Debasis Bagchi and Narasimman Gurusamy and Harold Swartz and Dipak Kumar Das},
  journal={Free radical biology & medicine},
  year={2008},
  volume={44 1},
  pages={82-90}
}
In this study, we determined the changes in the intracellular redox environment of the heart during ischemia and reperfusion and the effects of resveratrol on such changes. Because redox regulation by thioredoxin (Trx) plays a crucial role in signal transduction and cytoprotection against ROS, the effects of resveratrol on the changes in the amounts of thioredoxin were monitored in an attempt to determine the role of intracellular thioredoxin in resveratrol-mediated changes in intracellular… CONTINUE READING
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