Redox regulation of calcium ion channels: chemical and physiological aspects.

@article{Bogeski2011RedoxRO,
  title={Redox regulation of calcium ion channels: chemical and physiological aspects.},
  author={Ivan Bogeski and Reinhard Kappl and Carsten Kummerow and Rubin Gulaboski and Markus Hoth and Barbara A Niemeyer},
  journal={Cell calcium},
  year={2011},
  volume={50 5},
  pages={
          407-23
        }
}
Reactive oxygen species (ROS) are increasingly recognized as second messengers in many cellular processes. While high concentrations of oxidants damage proteins, lipids and DNA, ultimately resulting in cell death, selective and reversible oxidation of key residues in proteins is a physiological mechanism that can transiently alter their activity and function. Defects in ROS producing enzymes cause disturbed immune response and disease. Changes in the intracellular free Ca(2+) concentration are… CONTINUE READING

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