Redox metabolism in Trypanosoma cruzi: functional characterization of tryparedoxins revisited.

@article{Arias2013RedoxMI,
  title={Redox metabolism in Trypanosoma cruzi: functional characterization of tryparedoxins revisited.},
  author={Diego G. Arias and Vanina E M{\'a}rquez and Mar{\'i}a Laura Chiribao and Fernanda Ramos Gadelha and Carlos Robello and Alberto A. Iglesias and Sergio Adri{\'a}n Guerrero},
  journal={Free radical biology & medicine},
  year={2013},
  volume={63},
  pages={65-77}
}
Tryparedoxins (TXNs) are multipurpose oxidoreductases from trypanosomatids that transfer reducing equivalents from trypanothione to various thiol proteins. In Trypanosoma cruzi, two genes coding for TXN-like proteins have been identified: TXNI, previously characterized as a cytoplasmic protein, and TXNII, a putative tail-anchored membrane protein. In this work, we performed a comparative functional characterization of T. cruzi TXNs. Particularly, we cloned the gene region coding for the soluble… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…