Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics.

@article{Kalinowski2016RedoxCM,
  title={Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics.},
  author={Danuta S. Kalinowski and Christian Stefani and Shinya Toyokuni and Tomas Ganz and Gregory J Anderson and Nathan V Subramaniam and Debbie Trinder and John K Olynyk and Anita C. G. Chua and Patric J. Jansson and Sumit Sahni and Darius J. R. Lane and Angelica M. Merlot and Žaklina Kova{\vc}evi{\'c} and Michael L. H. Huang and C. Soon Lee and Des. R. Richardson},
  journal={Biochimica et biophysica acta},
  year={2016},
  volume={1863 4},
  pages={727-48}
}
Essential metals, such as iron and copper, play a critical role in a plethora of cellular processes including cell growth and proliferation. However, concomitantly, excess of these metal ions in the body can have deleterious effects due to their ability to generate cytotoxic reactive oxygen species (ROS). Thus, the human body has evolved a very well… CONTINUE READING