Redox cycling in iron uptake, efflux, and trafficking.

@article{Kosman2010RedoxCI,
  title={Redox cycling in iron uptake, efflux, and trafficking.},
  author={Daniel J Kosman},
  journal={The Journal of biological chemistry},
  year={2010},
  volume={285 35},
  pages={26729-35}
}
Aerobic organisms are faced with a dilemma. Environmental iron is found primarily in the relatively inert Fe(III) form, whereas the more metabolically active ferrous form is a strong pro-oxidant. This conundrum is solved by the redox cycling of iron between Fe(III) and Fe(II) at every step in the iron metabolic pathway. As a transition metal ion, iron can be "metabolized" only by this redox cycling, which is catalyzed in aerobes by the coupled activities of ferric iron reductases… CONTINUE READING
32 Citations
4 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

References

Publications referenced by this paper.
Showing 1-4 of 4 references

unpublished data. MINIREVIEW: Redox Cycling in Iron Uptake/Efflux/Trafficking

  • C. G. Holmberg, C. B. Laurell
  • AUGUST 27,
  • 2010

Redox Cycling in Iron Uptake/Efflux/Trafficking

  • E. M. Rees, D. J. Thiele
  • J. Biol. Chem. 282,
  • 2007

O.,Miret, S.,McGregor

  • A. T. McKie, G. Latunde-Dada
  • Biochem. Soc. Trans
  • 2002

587–603 MINIREVIEW: Redox Cycling in Iron Uptake/Efflux/Trafficking 26734 JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME

  • T. J. Stillman, P. D. Hempstead, +5 authors P. M. Harrison
  • J. Mol. Biol
  • 2001

Similar Papers

Loading similar papers…