Redox characterization of usnic acid and its cytotoxic effect on human neuron-like cells (SH-SY5Y).

@article{Rabelo2012RedoxCO,
  title={Redox characterization of usnic acid and its cytotoxic effect on human neuron-like cells (SH-SY5Y).},
  author={Thallita Kelly Rabelo and Fares Zeid{\'a}n-Chuli{\'a} and Laura Mil{\'a}n Vasques and Jo{\~a}o Paulo Almeida dos Santos and Ricardo Fagundes da Rocha and Matheus Augusto de Bittencourt Pasquali and Jos{\'e} Luiz Rybarczyk-Filho and Adriano Antunes Souza Ara{\'u}jo and Jos{\'e} Cl{\'a}udio Fonseca Moreira and Daniel Pens Gelain},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2012},
  volume={26 2},
  pages={
          304-14
        }
}
Usnic acid (UA) is the most common and abundant lichenic secondary metabolite with potential therapeutic application. Anti-inflammatory and antitumour properties have already been reported and UA-enriched extracts are widely used to treat several diseases in the folk medicine. First, we performed in silico evaluation of UA interactions with genes/proteins and important compounds for cellular redox balance and NO pathway. Then, we assessed UA redox properties against different reactive species… CONTINUE READING

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