Redox characteristics of the eukaryotic cytosol.

@article{LpezMirabal2008RedoxCO,
  title={Redox characteristics of the eukaryotic cytosol.},
  author={H. Reynaldo L{\'o}pez-Mirabal and Jakob R Winther},
  journal={Biochimica et biophysica acta},
  year={2008},
  volume={1783 4},
  pages={
          629-40
        }
}
  • H. Reynaldo López-Mirabal, Jakob R Winther
  • Published in Biochimica et biophysica acta 2008
  • Biology, Medicine
  • The eukaryotic cytoplasm has long been regarded as a cellular compartment in which the reduced state of protein cysteines is largely favored. Under normal conditions, the cytosolic low-molecular weight redox buffer, comprising primarily of glutathione, is highly reducing and reactive oxygen species (ROS) and glutathionylated proteins are maintained at very low levels. In the present review, recent progress in the understanding of the cytosolic thiol-disulfide redox metabolism and novel… CONTINUE READING

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