Redox biochemistry of hydrogen sulfide.

  title={Redox biochemistry of hydrogen sulfide.},
  author={Omer Kabil and Ruma Banerjee},
  journal={The Journal of biological chemistry},
  volume={285 29},
H(2)S, the most recently discovered gasotransmitter, might in fact be the evolutionary matriarch of this family, being both ancient and highly reduced. Disruption of gamma-cystathionase in mice leads to cardiovascular dysfunction and marked hypertension, suggesting a key role for this enzyme in H(2)S production in the vasculature. However, patients with inherited deficiency in gamma-cystathionase apparently do not present vascular pathology. A mitochondrial pathway disposes sulfide and couples… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS


Publications citing this paper.
Showing 1-10 of 147 extracted citations


Publications referenced by this paper.
Showing 1-2 of 2 references

hp://w w w D

  • G. D. Westrop, I. Georg, G. H. Coombs
  • J Biol Chem 284,
  • 2009

Disorders of Transsulfuration. in The Online Metabolic and Molecular Bases of Inherited Disease (Scriver

  • S. H. Mudd, H. L. Levy, J. P. Kraus
  • 2001

Similar Papers

Loading similar papers…