Redox balance influences differentiation status of neuroblastoma in the presence of all-trans retinoic acid

Abstract

Neuroblastoma is the most common extra-cranial solid tumor in childhood; and patients in stage IV of the disease have a high propensity for tumor recurrence. Retinoid therapy has been utilized as a means to induce differentiation of tumor cells and to inhibit relapse. In this study, the expression of a common neuronal differentiation marker [neurofilament M… (More)
DOI: 10.1016/j.redox.2015.11.012

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