Redox Signaling from and to Peroxisomes: Progress, Challenges, and Prospects.

  title={Redox Signaling from and to Peroxisomes: Progress, Challenges, and Prospects.},
  author={M. Fransen and Celien Lismont},
  journal={Antioxidants \& redox signaling},
  volume={30 1},
SIGNIFICANCE Peroxisomes are organelles that are best known for their role in cellular lipid and hydrogen peroxide (H2O2) metabolism. Emerging evidence suggests that these organelles serve as guardians and modulators of cellular redox balance, and that alterations in their redox metabolism may contribute to aging and the development of chronic diseases such as neurodegeneration, diabetes, and cancer. Recent Advances: H2O2 is an important signaling messenger that controls many cellular processes… Expand
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