Redox-Neutral Access to Sultams from 2-Nitrochalcones and Sulfur with Complete Atom Economy.

@article{Nguyen2017RedoxNeutralAT,
  title={Redox-Neutral Access to Sultams from 2-Nitrochalcones and Sulfur with Complete Atom Economy.},
  author={Thanh Binh Nguyen and Pascal Retailleau},
  journal={Organic letters},
  year={2017},
  volume={19 14},
  pages={
          3879-3882
        }
}
A catalyst-free, redox-neutral, and completely atom-economical synthesis of sultams by simply heating 2-nitrochalcones with elemental sulfur in 3-picoline or N-methylmorpholine is described. The S-N, C-S, and S═O bonds of the sulfonamide are efficiently formed between the nitrogen atom of the 2-nitro group and the α-carbon of the chalcones and elemental… CONTINUE READING