Redox Control of Signal Transduction, Gene Expression and Cellular Senescence

@article{Esposito2004RedoxCO,
  title={Redox Control of Signal Transduction, Gene Expression and Cellular Senescence},
  author={Franca Esposito and Rosario Ammendola and Raffaella Faraonio and Tommaso Russo and Filiberto Cimino},
  journal={Neurochemical Research},
  year={2004},
  volume={29},
  pages={617-628}
}
Reactive oxygen species (ROS) act as subcellular messengers in such complex cellular processes as mitogenic signal transduction, gene expression, regulation of cell proliferation, replicative senescence, and apoptosis. They serve to maintain cellular homeostasis and their production is under strict control. However, the mechanisms whereby ROS act are still obscure. Here we review recent advances in our understanding of signaling mechanisms and recent data about the involvement of ROS in: (i… CONTINUE READING