Redistribution of synaptophysin and synapsin I during alpha-latrotoxin- induced release of neurotransmitter at the neuromuscular junction

@article{TorriTarelli1990RedistributionOS,
  title={Redistribution of synaptophysin and synapsin I during alpha-latrotoxin- induced release of neurotransmitter at the neuromuscular junction},
  author={F Torri-Tarelli and Antonello Villa and Flavia Valtorta and Pietro De Camilli and Paul Greengard and Bruno Ceccarelli},
  journal={The Journal of Cell Biology},
  year={1990},
  volume={110},
  pages={449 - 459}
}
The distribution of two synaptic vesicle-specific phosphoproteins, synaptophysin and synapsin I, during intense quantal secretion was studied by applying an immunogold labeling technique to ultrathin frozen sections. In nerve-muscle preparations treated for 1 h with a low dose of alpha-latrotoxin in the absence of extracellular Ca2+ (a condition under which nerve terminals are depleted of both quanta of neurotransmitter and synaptic vesicles), the immunolabeling for both proteins was… CONTINUE READING

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