Redistribution of Tight Junction Proteins During EPEC Infection In Vivo

  title={Redistribution of Tight Junction Proteins During EPEC Infection In Vivo},
  author={Qiang Zhang and Qiurong Li and Chenyang Wang and Ning Li and Jie-shou Li},
Enteropathogenic Escherichia coli (EPEC) is a leading cause of diarrhea among infants. Tight junction plays a vital role in intestinal paracellular permeability by forming physical intercellular barriers in epithelial cells. However, the impact of this enteric pathogen on tight junctions in vivo has not been fully investigated. In the present study, the alterations in tight junctions following EPEC infection in vivo were investigated. Western blot analysis revealed that the tight junction… CONTINUE READING

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