Redistribution of Na+/H+ exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension.

@article{Yip1998RedistributionON,
  title={Redistribution of Na+/H+ exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension.},
  author={K P Yip and C Ming Tse and Alicia A McDonough and Donald J. Marsh},
  journal={American journal of physiology. Renal physiology},
  year={1998},
  volume={275 4},
  pages={F565-F575}
}
Redistribution of apical Na+/H+exchangers (NHE) in the proximal tubules as a plausible mechanism of pressure natriuresis was investigated with confocal immunofluorescence microscopy in Sprague-Dawley rats (SD), spontaneously hypertensive rats (SHR), and two-kidney, one-clip Goldblatt hypertensive rats (GH). NHE isoform NHE3 was localized in the brush border of proximal tubules in SD. Twenty minutes of induced acute hypertension (20-40 mmHg) resulted in a pronounced redistribution of isoform… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 44 extracted citations

Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3.

American journal of physiology. Renal physiology • 2015
View 1 Excerpt

Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure.

American journal of physiology. Regulatory, integrative and comparative physiology • 2010
View 4 Excerpts

Similar Papers

Loading similar papers…