Redistribution of GAP-43 during growth cone development in vitro; immunocytochemical studies.

@article{Burry1991RedistributionOG,
  title={Redistribution of GAP-43 during growth cone development in vitro; immunocytochemical studies.},
  author={Richard W. Burry and James J Lah and Daniel M. Gaines Caroline C. Hayes},
  journal={Journal of neurocytology},
  year={1991},
  volume={20 2},
  pages={133-44}
}
The growth-associated protein GAP-43 (B-50, F1, pp46), has been found in elongating axons during development and regeneration, and has also been associated with synaptic plasticity in mature neurons. We have examined the loss of GAP-43 labelling from cerebellar granule cells with immunocytochemical localization of a polyclonal antibody to GAP-43. One day after plating, the plasma membrane of cell bodies, neurites and growth cones were all labelled with anti-GAP-43. By 10 days, most of the cell… CONTINUE READING
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