• DOI:10.1093/molehr/gar044
Corpus ID: 6932641

Rediscovering sperm ion channels with the patch-clamp technique.

@article{Kirichok2011RediscoveringSI,
  title={Rediscovering sperm ion channels with the patch-clamp technique.},
  author={Yuriy Kirichok and Polina V Lishko},
  journal={Molecular human reproduction},
  year={2011},
  volume={17 8},
  pages={
          478-99
        }
}

Yuriy Kirichok, Polina V Lishko

Published in Molecular human reproduction 2011

Medicine, Biology

Upon ejaculation, mammalian spermatozoa have to undergo a sequence of physiological transformations within the female reproductive tract that will allow them to reach and fertilize the egg. These include initiation of motility, hyperactivation of motility and perhaps chemotaxis toward the egg, and culminate in the acrosome reaction that permits sperm to penetrate the protective vestments of the egg. These physiological responses are triggered through the activation of sperm ion channels that… CONTINUE READING

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