Rediscovering sperm ion channels with the patch-clamp technique.

@article{Kirichok2011RediscoveringSI,
  title={Rediscovering sperm ion channels with the patch-clamp technique.},
  author={Yuriy Kirichok and Polina V Lishko},
  journal={Molecular human reproduction},
  year={2011},
  volume={17 8},
  pages={
          478-99
        }
}
  • Yuriy Kirichok, Polina V Lishko
  • Published in Molecular human reproduction 2011
  • Medicine, Biology
  • Upon ejaculation, mammalian spermatozoa have to undergo a sequence of physiological transformations within the female reproductive tract that will allow them to reach and fertilize the egg. These include initiation of motility, hyperactivation of motility and perhaps chemotaxis toward the egg, and culminate in the acrosome reaction that permits sperm to penetrate the protective vestments of the egg. These physiological responses are triggered through the activation of sperm ion channels that… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 49 CITATIONS

    Lipid modulation of calcium flux through CaV2.3 regulates acrosome exocytosis and fertilization.

    VIEW 11 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Sperm patch-clamp.

    VIEW 9 EXCERPTS
    CITES BACKGROUND

    In silico identification of the genes for sperm-egg interaction in the internal fertilization of the newt Cynops pyrrhogaster.

    VIEW 2 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Oviduct Binding and Elevated Environmental pH Induce Protein Tyrosine Phosphorylation in Stallion Spermatozoa1

    VIEW 3 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Onion peel extract and its constituent, quercetin inhibits human Slo3 in a pH and calcium dependent manner

    VIEW 1 EXCERPT
    CITES BACKGROUND

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 172 REFERENCES

    The epididymis, cytoplasmic droplets and male fertility.

    VIEW 7 EXCERPTS
    HIGHLY INFLUENTIAL

    Control of hyperactivation in sperm.

    VIEW 13 EXCERPTS
    HIGHLY INFLUENTIAL

    KSper, a pH-sensitive K+ current that controls sperm membrane potential.

    VIEW 24 EXCERPTS

    Sperm transport in the female reproductive tract.

    VIEW 6 EXCERPTS
    HIGHLY INFLUENTIAL

    Calcium channels and Ca2+ fluctuations in sperm physiology.

    VIEW 7 EXCERPTS
    HIGHLY INFLUENTIAL