Rediscovering natural products as a source of new drugs.

  title={Rediscovering natural products as a source of new drugs.},
  author={Frank Koehn and Guy T Carter},
  journal={Discovery medicine},
  volume={5 26},
Extract: Since the very beginnings of human medicine, physicians have relied on chemical compounds produced by animals, plants and microorganisms, so-called natural products, to treat diseases. Natural products are directly or indirectly responsible for roughly one-half of all drugs currently in use. Of the 877 small-molecule new drug molecules introduced between 1981 and 2002, 49% were natural products or natural product analogs. Despite the great success of the 70s and 80s, the pharmaceutical… CONTINUE READING


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