Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants

@article{Wu2006RedirectionOC,
  title={Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants},
  author={Shuiqin Wu and M. Schalk and Anthony J Clark and R. B. Miles and R. Coates and J. Chappell},
  journal={Nature Biotechnology},
  year={2006},
  volume={24},
  pages={1441-1447}
}
Terpenes constitute a distinct class of natural products1 that attract insects, defend against phytopathogenic microbes and combat human diseases. However, like most natural products, they are usually made by plants and microbes in small amounts and as complex mixtures. Chemical synthesis is often costly and inefficient, and may not yield enantiomerically pure terpenes, whereas large-scale microbial production requires expensive feedstocks. We engineered high-level terpene production in tobacco… Expand
Metabolic engineering of higher plants and algae for isoprenoid production.
Overcoming Bottlenecks for Metabolic Engineering of Sesquiterpene Production in Tomato Fruits
High-Level Patchoulol Biosynthesis in Artemisia annua L.
Engineering triterpene metabolism in tobacco
Engineering triterpene metabolism in the oilseed of Arabidopsis thaliana
Harnessing yeast subcellular compartments for the production of plant terpenoids.
Chloroplastic metabolic engineering coupled with isoprenoid pool enhancement for committed taxanes biosynthesis in Nicotiana benthamiana
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