Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants

@article{Wu2006RedirectionOC,
  title={Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants},
  author={Shuiqin Wu and Michel Schalk and Anthony J Clark and R. Brandon Miles and Robert M. Coates and Joseph Chappell},
  journal={Nature Biotechnology},
  year={2006},
  volume={24},
  pages={1441-1447}
}
Terpenes constitute a distinct class of natural products1 that attract insects, defend against phytopathogenic microbes and combat human diseases. However, like most natural products, they are usually made by plants and microbes in small amounts and as complex mixtures. Chemical synthesis is often costly and inefficient, and may not yield enantiomerically pure terpenes, whereas large-scale microbial production requires expensive feedstocks. We engineered high-level terpene production in tobacco… 
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