Rediocides A and G as Potential Antitoxins Against Cobra Venom

@article{Utsintong2009RediocidesAA,
  title={Rediocides A and G as Potential Antitoxins Against Cobra Venom},
  author={M. Utsintong and Atchara Kaewnoi and W. Leelamanit and A. Olson and O. Vajragupta},
  journal={Chemistry \& Biodiversity},
  year={2009},
  volume={6}
}
Rediocides A and G, the principle components of Trigonostemon reidioides (Kurz) Craib, which is known as Lotthanong in Thai, were investigated for a detoxification mechanism against Naja kaouthia venom by in silico, in vitro, and in vivo methods. Molecular dockings of α‐cobratoxin with rediocides A and G were performed, and the binding energies were found to be −14.17 and −14.14 kcal/mol, respectively. Rediocides bind to α‐cobratoxin at the same location as α‐cobratoxin binds to the nicotinic… Expand
Targeting CD155 by rediocide-A overcomes tumour immuno-resistance to natural killer cells

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