Redefining the classification of AMPA-selective ionotropic glutamate receptors.

@article{Bowie2012RedefiningTC,
  title={Redefining the classification of AMPA-selective ionotropic glutamate receptors.},
  author={Derek Bowie},
  journal={The Journal of physiology},
  year={2012},
  volume={590 1},
  pages={49-61}
}
AMPA-type ionotropic glutamate receptors (iGluRs) represent the major excitatory neurotransmitter receptor in the developing and adult vertebrate CNS. They are crucial for the normal hardwiring of glutamatergic circuits but also fine tune synaptic strength by cycling into and out of synapses during periods of sustained patterned activity or altered homeostasis. AMPARs are grouped into two functionally distinct tetrameric assemblies based on the inclusion or exclusion of the GluA2 receptor… CONTINUE READING

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