Redefining response in overactive bladder syndrome.

  title={Redefining response in overactive bladder syndrome.},
  author={Christopher K. Payne and Con Kelleher},
  journal={BJU international},
  volume={99 1},
OBJECTIVE To evaluate three potential definitions of treatment response in overactive bladder (OAB) syndrome, based on the International Continence Society (ICS) definition of OAB, using pooled data from two large clinical trials of the antimuscarinic agent solifenacin succinate. PATIENTS AND METHODS As the ICS definition of OAB does not rely on urodynamic observations for a diagnosis, the use of composite endpoints, such as in the definitions examined here, might provide a more relevant… CONTINUE READING


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