Red wine antioxidant resveratrol-modified cardiac stem cells regenerate infarcted myocardium

@inproceedings{Gurusamy2010RedWA,
  title={Red wine antioxidant resveratrol-modified cardiac stem cells regenerate infarcted myocardium},
  author={Narasimman Gurusamy and Diptarka Ray and Istvan Lekli and Dipak Kumar Das},
  booktitle={Journal of cellular and molecular medicine},
  year={2010}
}
To study the efficiency of maintaining the reduced tissue environment via pre-treatment with natural antioxidant resveratrol in stem cell therapy, we pre-treated male Sprague-Dawley rats with resveratrol (2.5 mg/kg/day gavaged for 2 weeks). After occlusion of the left anterior descending coronary artery (LAD), adult cardiac stem cells stably expressing EGFP were injected into the border zone of the myocardium. One week after the LAD occlusion, the cardiac reduced environment was confirmed in… CONTINUE READING
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