Red ginseng represses hypoxia-induced cyclooxygenase-2 through sirtuin1 activation.

@article{Lim2015RedGR,
  title={Red ginseng represses hypoxia-induced cyclooxygenase-2 through sirtuin1 activation.},
  author={Wonchung Lim and Myeong Kuk Shim and Sikwan Kim and Youngjoo Lee},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2015},
  volume={22 6},
  pages={597-604}
}
BACKGROUND Korean red ginseng (KRG) is a traditional herbal medicine made by steaming and drying the fresh ginseng, leading to chemical transformation of some components by heat. It ameliorates various inflammatory diseases and strengthens the endocrine, immune, and central nervous systems. The cyclooxygenase-2 (COX-2)/prostaglandin E2 pathway in hypoxic cancer cells has important implications for stimulation of inflammation and tumorigenesis. PURPOSE In this study we examined the effects and… CONTINUE READING
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