Red cell perturbations by amyloid beta-protein.

@article{Jayakumar2003RedCP,
  title={Red cell perturbations by amyloid beta-protein.},
  author={Rajadas Jayakumar and John W. Kusiak and Francis J. Chrest and Andrew A Demehin and Jayaraman Murali and Robert P. Wersto and Nagababu Enika and Lukebabu Ravi and Joseph M. Rifkind},
  journal={Biochimica et biophysica acta},
  year={2003},
  volume={1622 1},
  pages={
          20-8
        }
}
Amyloid beta-protein (A beta) accumulation in brain is thought to be important in causing the neuropathology of Alzheimer's disease (AD). A beta interactions with both neurons and microglial cells play key roles in AD. Since vascular deposition of A beta is also implicated in AD, the interaction of red cells with these toxic aggregates gains importance. However, the effects of A beta interactions with red blood cells are less well understood. Synthetic amyloid beta-protein (1-40) was labeled… CONTINUE READING

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