Red cell genotyping and the future of pretransfusion testing.

  title={Red cell genotyping and the future of pretransfusion testing.},
  author={David J Anstee},
  volume={114 2},
Over the past 20 years the molecular bases of almost all the major blood group antigens have been determined. This research has enabled development of DNA-based methods for determining blood group genotype. The most notable application of these DNA-based methods has been for determining fetal blood group in pregnancies when the fetus is at risk for hemolytic disease of the fetus and newborn. The replacement of all conventional serologic methods for pretransfusion testing by molecular methods is… 

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