Red blood cell aggregation and microcirculation in rat cremaster muscle.

@article{Vicaut1994RedBC,
  title={Red blood cell aggregation and microcirculation in rat cremaster muscle.},
  author={{\'E}ric Vicaut and Xiaohong Hou and Laurent Decuyp{\`e}re and Alain Taccoen and M A Duvelleroy},
  journal={International journal of microcirculation, clinical and experimental},
  year={1994},
  volume={14 1-2},
  pages={14-21}
}
Using intravital microscopy of the rat cremaster muscle, we studied the effects of changing red blood cell (RBC) aggregation on RBC arteriolar velocity and perfused capillary density (PCD). To modify RBC aggregation, 2 and/or 10% dextran (molecular weights 40,000, 70,000 or 480,000) or fresh rat plasma was infused into adult male rats via a normovolemic hemodilution procedure. The high-molecular-weight dextrans (70,000 and 480,000) both induced RBC hyperaggregation associated with similar dose… CONTINUE READING