Red 25, a protein that binds specifically to the sterol regulatory region in the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

@article{Osborne1992Red2A,
  title={Red 25, a protein that binds specifically to the sterol regulatory region in the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.},
  author={Timothy F. Osborne and Mary K Bennett and K Rhee},
  journal={The Journal of biological chemistry},
  year={1992},
  volume={267 26},
  pages={18973-82}
}
A protein that binds to the sterol regulatory region of the hamster promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase has been identified. All of the DNA bases crucial to the binding of this protein were previously shown to be essential for sterol regulation of the intact promoter in cultured cells. This low abundance protein, called Red 25, has been purified from nuclear extracts of hamster liver by a series of standard chromatographic techniques coupled with a DNA affinity step… CONTINUE READING

References

Publications referenced by this paper.

Purification of Red 25 Protein

E d . Chem
J. Biol. Chern. 266, • 1988

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