Recycling pathways of glucosylceramide in BHK cells: distinct involvement of early and late endosomes.

@article{Kok1992RecyclingPO,
  title={Recycling pathways of glucosylceramide in BHK cells: distinct involvement of early and late endosomes.},
  author={Jan Willem Kok and Karin Hoekstra and Sinikka Eskelinen and Dick Hoekstra},
  journal={Journal of cell science},
  year={1992},
  volume={103 ( Pt 4)},
  pages={1139-52}
}
Recycling pathways of the sphingolipid glucosylceramide were studied by employing a fluorescent analog of glucosylceramide, 6(-)[N-(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoylglucosyl sphingosine (C6-NBD-glucosylceramide). Direct recycling of the glycolipid from early endosomes to the plasma membrane occurs, as could be shown after treating the cells with the microtubule-disrupting agent nocodazole, which causes inhibition of the glycolipid's trafficking from peripheral early endosomes to… CONTINUE READING
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A nonexchangeable fluorescent phospholipid analog as a membrane traffic marker of the endocytic pathway

  • J. W. Kok, M. ter Beest, G. Scherphof, D. Hoekstra
  • Eur . J . Cell Biol .
  • 1990
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