Recycling endosomes in apical plasma membrane domain formation and epithelial cell polarity.

@article{Golachowska2010RecyclingEI,
  title={Recycling endosomes in apical plasma membrane domain formation and epithelial cell polarity.},
  author={Magdalena R Golachowska and Dick Hoekstra and Sven C D van IJzendoorn},
  journal={Trends in cell biology},
  year={2010},
  volume={20 10},
  pages={618-26}
}
Recycling endosomes have taken central stage in the intracellular sorting and polarized trafficking of apical and basolateral plasma membrane components. Molecular players in the underlying mechanisms are now emerging, including small GTPases, class V myosins and adaptor proteins. In particular, defects in the expression or function of these recycling endosome-associated and endosome-regulating proteins have been implicated in cell surface polarity defects and diseases, including microvillus… CONTINUE READING