Recycling and refilling of transmitter quanta at the frog neuromuscular junction

  title={Recycling and refilling of transmitter quanta at the frog neuromuscular junction},
  author={W. Kloot and Cesare Colasante and R. Cameron and J. Molg{\'o}},
  journal={The Journal of Physiology},
  • W. Kloot, Cesare Colasante, +1 author J. Molgó
  • Published 2000
  • Chemistry, Medicine
  • The Journal of Physiology
  • Fluorescent dyes have been used at the frog neuromuscular junction to label synaptic vesicular membrane. Retrieved membrane is reformed into vesicles, which are released along with pre‐existing vesicles. Consequently, if vesicular refilling with acetylcholine (ACh) is depressed by inhibitors, two sizes of quanta should be released: normal and smaller. As recycling continues the fraction of smaller size quanta should increase exponentially. We enhanced the rate of quantal release by elevating… CONTINUE READING
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