Recursive partitioning for tumor classification with gene expression microarray data.

  title={Recursive partitioning for tumor classification with gene expression microarray data.},
  author={Heping Zhang and Chye Yun Yu and Burton Singer and Momiao Xiong},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={98 12},
Precise classification of tumors is critically important for cancer diagnosis and treatment. It is also a scientifically challenging task. Recently, efforts have been made to use gene expression profiles to improve the precision of classification, with limited success. Using a published data set for purposes of comparison, we introduce a methodology based on classification trees and demonstrate that it is significantly more accurate for discriminating among distinct colon cancer tissues than… CONTINUE READING


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