Recurring views on the structure and function of the cytoskeleton: a 300-year epic.
@article{Frixione2000RecurringVO, title={Recurring views on the structure and function of the cytoskeleton: a 300-year epic.}, author={Eugenio Frixione}, journal={Cell motility and the cytoskeleton}, year={2000}, volume={46 2}, pages={ 73-94 } }
Some unnoticed or seldom remembered precedents of current views on biological motion and its structural bases are briefly outlined, followed by a concise recapitulation of how the present theory has been constructed in the last few decades. It is shown that the evolution of the concept of fibers as main constituents of living matter led to hypothesizing microscopic structures closely resembling microtubules in the 18th century. At the beginning of this period, fibers sliding over each other and…
97 Citations
Sigmund Freud's Contribution to the History of the Neuronal Cytoskeleton
- BiologyJournal of the history of the neurosciences
- 2003
Sigmund Freud was able to discern separate fine fibrils following straight courses within the nerve fibers, as well as concentric loops of striae surrounding the nuclei and converging towards the processes of the cell bodies in crayfish nervous tissue.
The Cytoskeleton of Nerve Cells in Historic Perspective
- Biology
- 2012
The history of how the biologically important concept of a cytoskeleton emerged is to a large extent a history of the neurocytoskeleton.
Muscle microanatomy and its changes during contraction: the legacy of William Bowman (1816–1892)
- BiologyJournal of Muscle Research & Cell Motility
- 2005
It is shown that not only Bowman succeeded in establishing the true architecture of striated muscle fibres to the extent possible with the most advanced technology available in his day but also in correctly describing the basic microstructural changes associated with contraction.
Computational and Modeling Strategies for Cell Motility
- Biology
- 2012
The generalization of such a nonlinear limit cycle mechanism to include 3D spatial substructures consistent with cell mechanics, and biochemical kinetics and diffusion, charts a path that the group has elected.
Cajal's second great battle for the neuron doctrine: the nature and function of neurofibrils
- BiologyBrain Research Reviews
- 2009
MDI: integrity index of cytoskeletal fibers observed by AFM
- Physics
- 2016
Abstract.The Modified Directional Index (MDI) is a form factor of the angular spectrum computed from the 2D Fourier transform of an image marking the prevalence of rectilinear features throughout the…
Neura, nerves, nerve fibers, neurofibrils, microtubules: multidimensional routes of pain, pleasure, and voluntary action in images across the ages.
- BiologyProgress in brain research
- 2013
The prehistory of the cytoskeleton concept
- BiologyCytoskeleton
- 2014
Here we discuss how the concept and the name of cytoskeleton were generated and started to evolve over the last two centuries into what is presently a basic topic of modern biology. We also attempt…
Active biological materials.
- Materials ScienceAnnual review of physical chemistry
- 2009
Results indicate that a complex interplay between length scales and timescales underlies the mechanical responses of these systems and that energy consumption, as manifested in molecular motor activity and cytoskeletal filament growth, can drive transitions between distinct material states.
References
SHOWING 1-10 OF 406 REFERENCES
RETICULAR ORGANIZATIONS WITHIN THE STRIATED MUSCLE CELL
- HistoryThe Journal of biophysical and biochemical cytology
- 1961
It is shown that workers in the early years of this century by no means ignored or abandoned the unfinished lines of approach inherited from the last, and at the turn of the century there was scarcely a single aspect of muscle organization that was not entirely controversial.
MICROTUBULE RESEARCH JN PERSPECTIVE
- Biology
- 1975
The subject of this conference may have a short history but it has a long memory; microtubule research began long before microtubules were discovered; many of the questions asked were asked by the ancestors; the microscopic approach won out by reason of successes that still earn the authors' awe.
A personal view of muscle and motility mechanisms.
- PhysicsAnnual review of physiology
- 1996
How synchrotron radiation has made it possible to obtain detailed structural information about contracting muscle with millisecond time resolution is described and some of the recent major advances in the field are discussed and the prospects of reaching a full understanding of the contraction mechanism are discussed.
A MOVING IMAGE OF FLAGELLA: NEWS AND VIEWS ON THE MECHANISMS INVOLVED IN AXONEMAL BEATING
- BiologyCell biology international
- 1996
The present study puts forward ideas as to how these organelles have been highly conserved throughout eucaryotic evolution, and concludes with suggestions for further fields of investigation into this unique mechanical device used for cell movement.
THE ULTRASTRUCTURE OF FLAGELLAR FIBRILS
- Biology, ChemistryThe Journal of cell biology
- 1963
The tips of rat sperm tails were slightly frayed by mechanical agitation, thus exposing the fibrils, which were then studied by electron microscopy after negative staining, and it can be inferred that they possessed considerable mechanical strength.
THE INTERACTION OF MYOSIN AND ADENOSINETRIPHOSPHATE
- BiologyAnnals of the New York Academy of Sciences
- 1947
It is established that myosin can no longer be regarded as an inert protein serving merely as the building blocks of the muscle fibril, but is, in all probability, a functional basis for the muscular activity.
Microfilaments in Cellular and Developmental Processes
- BiologyScience
- 1971
The overall conclusion is that a broad spectrum of cellular and developmental processes are caused by contractile apparatuses that have at least the common feature of being sensitive to cytochalasin.
Cell Motility by Labile Association of Molecules
- BiologyThe Journal of general physiology
- 1967
This article summarizes the current views on the dynamic structure of the mitotic spindle and its relation to mitotic chromosome movements based on measurements of birefringence of spindle fibers in living cells, normally developing or experimentally modified by various physical and chemical agents.
Microtubules: a brief historical perspective.
- BiologyJournal of structural biology
- 1997
Research on the morphology and molecular structure of microtubules spans 3 decades and is now entering an exciting new "biophysical" era, as described in this issue.
Cytoplasmic contractile proteins
- BiologyThe Journal of cell biology
- 1981
Some of the important events in the growth of cytoplasmic contractile protein research are highlighted and some future trends are forecast to be forecast.