Recurrent typhlitis

  title={Recurrent typhlitis},
  author={Richard D. Keidan and James Fanning and Robert A. Gatenby and James L. Weese},
  journal={Diseases of the Colon \& Rectum},
Neutropenic typhlitis is a frequently fatal disease most commonly reported in leukemics. The authors have treated eight such patients over the last 18 months. All patients had abdominal pain and sepsis during chemotherapy-induced neutropenia. CT scanning was diagnostic in six patients thought to have typhlitis. Two patients were not diagnosed before exploratory laparotomy. The authors have found nonoperative treatment highly effective in patients who do not manifest signs of peritonitis… 

Typhlitis in children with cancer: a 30-year experience.

Computed tomography and/or ultrasonography should be performed in all neutropenic patients with right-lower-quadrant signs to permit prompt diagnosis and treatment of typhlitis.

Neutropenic enterocolitis. Clinical diagnosis and treatment

Review of the consultation records of the Gastrointestinal Surgical Oncology service at Roswell Park Memorial Institute from 1982 to 1987 revealed 22 patients with a finical diagnosis of neutropenic enterocolitis, which must be considered a diagnosis of exclusion.

Successful conservative treatment of neutropenic enterocolitis complicating taxane-based chemotherapy: a report of five cases.

Clinical and radiologic findings supported the diagnosis of acute neutropenic enterocolitis, a severe complication of taxane-based chemotherapy, and it is concluded that early diagnosis and appropriate conservative treatment leads to complete recovery.

The surgical choice in neutropenic patients with hematological disorders and acute abdominal complications.

The most critical patients were those affected by neutropenic enterocolitis and acute cholecystitis, and emergency surgical treatment may be safely carried out in patients with hematological diseases presenting with an acute abdomen.

A Case of Typhlitis Developed after Chemotherapy with Irinotecan and Cisplatin in a Patient with Small Cell Lung Carcinoma

The first case of typhlitis developed after chemotherapy combining irinotecan and cisplatin in a patient with SCLC is reported, mainly used in colon cancer and small cell lung carcinoma.

Typhlitis as the initial presentation of acute lymphocytic leukemia - A case report

It is suggested that typhlitis may present as an initial manifestation of ALL and Giardia lamblia may play a role in its pathogenesis.

Neutropenic enterocolitis: A continuing medical and surgical challenge

  • N. Machado
  • Medicine
    North American journal of medical sciences
  • 2010
Clinicians should be acutely aware of the association of neutropenic enterocolitis with chemotherapy for the outcome would depend significantly on an early and appropriate treatment either conservative or surgical based on the literature review.

Neutropenic Enterocolitis: Is There Aright Timing for Surgery? Assessment of a Clinical Case

A case of neutropenic enterocolitis is analyzed which occurred in a patient with acute myeloid leukemia during chemotherapy and it is suggested that, as well as intestinal wall thickness, hemodynamic worsening should be considered an indication for surgery.

Variant neutropenic enterocolitis presenting as acute appendicitis.

It is reported that the first case of NE with isolated appendiceal involvement in a non-oncologic neutropenic patient who was managed successfully medically is reported and neutropenia is formally recognized as a variant of NE and differentiate it from acute non-neutropenic appendicitis.



The medical and surgical management of typhlitis in children with acute nonlymphocytic (myelogenous) leukemia

Five patients required surgical intervention for typhlitis or its sequelae and one for acute appendicitis, and among the 21 patients managed medically, there was 1 death resulting from Typhlitis in a patient in whom surgery was deferred because of her multiple failures to enter remission.

Typhlitis: selective surgical management.

Typhlitis. A treatable cause of recurrent septicemia.

The following case report suggests that recurrent bacteremia with different organisms may be a sign of early typhlitis, and, to the best of the authors' knowledge, is the first reported antemortem diagnosis of Typhlitis in a patient with aplastic anemia.

Typhlitis in acute leukemia. Successful treatment by early surgical intervention

A patient in whom the clinical diagnosis of typhlitis led to early operation, with intensive blood component support, is reported, suggesting that such an approach might improve the usually grim prognosis in patients whose underlying malignancy offers a clear chance for remission.

Neutropenic typhlitis in adults.

Because this will usually be done on an emergency basis in a very ill patient with unprepared bowel, a two-stage procedure rather than primary anastomosis is advisable.

Typhlitis: a treatable complication of acute leukemia therapy.

It is strongly recommend that laparotomy be considered in selected patients with typhlitis occurring as a complication of treated leukemia, and close oncologic/surgical teamwork is stressed as the patient is followed closely into the time frame when the decision is made whether to operate.

Typhlitis in acute leukemia.

A patient in whom the clinical diagnosis of typhlitis led to early operation, with intensive blood component support, is reported, suggesting that such an approach might improve the usually grim prognosis in patients whose underlying malignancy offers a clear chance for remission.

Typhlitis: a complication of leukemia in childhood.

A very interesting clinical, roentgenographic, and pathologic lesion is presented which is found terminally in both treated leukemics who are agranulocytic and in patients with terminal aplastic

Necrotizing enterocolitis in leukemia.

Clinical findings were fever, diarrhea, ileus, and abdominal pain, and peritonitis and shock developed later, and treatment in two cases was unsuccessful, and all patients died.

Neutropenic enterocolitis in adults. Review of the literature and assessment of surgical intervention.

We have reported two cases of neutropenic enterocolitis (one of them being the first reported case occurring in a patient with multiple myeloma), which is a necrotizing lesion in the gastrointestinal