Recurrent Inguinal Hernia: Disease of the Collagen Matrix?

  title={Recurrent Inguinal Hernia: Disease of the Collagen Matrix?},
  author={Hong Zheng and Zhongyi Si and Reiner Kasperk and Rhanjit S. Bhardwaj and Volker Schumpelick and Uwe Klinge and Bernd Klosterhalfen},
  journal={World Journal of Surgery},
The aim of this study was to investigate the collagen matrix in recurrent inguinal hernias. Total ribonucleic acid (RNA) was extracted from skin fibroblasts of three groups (control group I = healthy skin; control group II = plain skin scar; recurrent inguinal hernia group = skin of recurrent inguinal hernias; each n = 5). Reverse transcription-polymerase chain reaction (RT-PCR) and Northern blot analysis were used to investigate the expression of procollagen type I/- III, MMP-1, and MMP-13… CONTINUE READING
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