Recurrent Herpes Labialis, Recurrent Aphthous Ulcers, and the Menstrual Cycle

@article{Segal1974RecurrentHL,
  title={Recurrent Herpes Labialis, Recurrent Aphthous Ulcers, and the Menstrual Cycle},
  author={A L Segal and Aaron Honori Katcher and Vernon J. Brightman and M F Miller},
  journal={Journal of Dental Research},
  year={1974},
  volume={53},
  pages={797 - 803}
}
A prospective study of 104 student nurses determined the frequency of recurrent herpes labialis and recurrent aphthous ulcers within the menstrual cycle. Each nurse kept daily calendars recording inter alia menses and episodes of lesions. Episodes of aphthae were not associated with any specific intervals in the menstrual cycle. There was a greater than expected incidence of episodes of herpetic lesions in the eight days preceding the onset of menses. 
Incidence of recurrent herpes labialis and upper respiratory infection: a prospective study of the influence of biologic, social and psychologic predictors.
TLDR
Timing of RHL episodes was not related to phase of the menstrual cycle, and measures of previous experience with RHL accounted for the largest fraction of the explained variance, followed by upper respiratory infection rate, socioeconomic status, and mood trait, in order of declining influence. Expand
Recurrent aphthous stomatitis: current concepts of etiology, pathogenesis and management.
  • C. Scully, S. Porter
  • Medicine
  • Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • 1989
Recurrent aphthous stomatitis (RAS) is a common oral disorder, however, despite detailed clinical, immunologic, hematologic and microbiologic investigation, the etiology of RAS remains unknown. AtExpand
Recurrent aphthous stomatitis.
TLDR
Recurrent aphthous stomatitis is a common disorder affecting 5% to 66% of examined adult patient groups, and children of higher socioeconomic status may be more commonly affected that those from low socioeconomic groups. Expand
Aphthous ulcerations
Recurrent aphthous stomatitis (RAS) is a chronic condition, usually with a childhood or adolescent onset and with a tendency to diminish in frequency and severity with age. Most patients areExpand
Recurrent aphthous ulcers today: a review of the growing knowledge.
TLDR
Different aetiologies and mechanisms might be operative in the aetiopathogenesis of aphthous ulceration, but pain, recurrence, self-limitation of the condition, and destruction of the epithelium seem to be the ultimate outcomes. Expand
Recurrent aphthous stomatitis.
TLDR
The clinical features, contributing etiologic factors, and etiopathogenesis of RAS and Behcet's syndrome are reviewed and therapeutic considerations and strategies essential to management of patients suffering from recurrent mouth ulcers are described. Expand
Aphthous stomatitis—an overview of aetiopathogenesis and management
TLDR
Current data concerning clinical and aetiopathological aspects of RAS and details of management are reviewed. Expand
Number VI Recurrent aphthous stomatitis
TLDR
Treatment of RAS remains unsatisfactory, as most therapies only reduce the severity of the ulceration and do not stop recurrence, but drugs, especially non-steroidal anti-inflammatory drugs and nicorandil can often control RAS. Expand
Is aphthous stomatitis associated with menstrual cycle in women?
TLDR
To establish the prevalence both of aphthae in women and of associations between Aphthae and menstrual cycle and to establish the importance of these associations in women's menstrual cycle. Expand
Recurrent aphthous stomatitis
TLDR
A detailed review of the current knowledge of the etiology, pathogenesis, and management of RAS is provided. Expand
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References

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TLDR
Evidence suggests that there is an endocrine factor in recurrences, which are not prevented by any treatment hitherto described, and œstrogen was given to 43 female patients with recurrent aphthous ulceration. Expand
Prediction of the Incidence of Recurrent Herpes Labialis and Systemic Illness from Psychological Measurements
TLDR
Measures of social assets and psychological discomfort added significant predictive information when used in combination with measures of susceptibility to RHL (antibody titer or frequency of RHL determined by history). Expand
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TLDR
Clinical and experimental findings seem, however, definitely to establish the occurrence of this condition of hypersensitivity to endogenous hormones in man. Expand
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