Recurrent Herpes Labialis, Recurrent Aphthous Ulcers, and the Menstrual Cycle

@article{Segal1974RecurrentHL,
  title={Recurrent Herpes Labialis, Recurrent Aphthous Ulcers, and the Menstrual Cycle},
  author={Arthur L. Segal and Aaron Honori Katcher and Vernon J. Brightman and Michael F. Miller},
  journal={Journal of Dental Research},
  year={1974},
  volume={53},
  pages={797 - 803}
}
A prospective study of 104 student nurses determined the frequency of recurrent herpes labialis and recurrent aphthous ulcers within the menstrual cycle. Each nurse kept daily calendars recording inter alia menses and episodes of lesions. Episodes of aphthae were not associated with any specific intervals in the menstrual cycle. There was a greater than expected incidence of episodes of herpetic lesions in the eight days preceding the onset of menses. 

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