Recurrent Acute Nitrofurantoin‐Induced Pulmonary Toxicity

  title={Recurrent Acute Nitrofurantoin‐Induced Pulmonary Toxicity},
  author={E. M. Williams and D. Triller},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  • E. M. Williams, D. Triller
  • Published 2006
  • Medicine
  • Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
  • Nitrofurantoin may be used for prophylaxis of recurrent urinary tract infections in women; however, this agent has been associated with acute, subacute, and chronic pulmonary adverse reactions. The acute reaction occurs in about 1/5000 women after their first exposure to the drug. We report the occurrence of two successive, highly probable (by Naranjo score) nitrofurantoin‐induced acute pulmonary reactions in the same patient. On day 4 of prophylaxis with nitrofurantoin 100 mg/day (to prevent… CONTINUE READING
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