Recurrent/metastatic thyroid carcinomas false negative for serum thyroglobulin but positive by posttherapy I-131 whole body scans

@article{Park2008RecurrentmetastaticTC,
  title={Recurrent/metastatic thyroid carcinomas false negative for serum thyroglobulin but positive by posttherapy I-131 whole body scans},
  author={Eun-kyung Park and June-Key Chung and Il Han Lim and Do Joon Park and Dong Soo Lee and Myung Chul Lee and Bo Youn Cho},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2008},
  volume={36},
  pages={172-179}
}
Serum Tg and I-131 WBS have been used to detect recurrent and metastatic thyroid cancers postoperatively. Tg is known to be more sensitive than I-131 WBS, and therefore, false-negative WBS cases with elevated Tg levels are frequently found. However, the clinical characteristics of false-negative Tg cases with positive WBS have not been clarified. The authors evaluated 824 postoperative patients with differentiated thyroid carcinoma who underwent post-ablation/therapy I-131 WBS. Tg negativity… CONTINUE READING
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