Recurrence risk to offspring in extended multiplex schizophrenia pedigrees from a Pacific Island isolate.

Abstract

Genetic transmission plays a major role in the pathogenesis of schizophrenia. Family, twin, and adoption studies have consistently shown that risks in relatives are many times greater than the general population risk of approximately 1%. McGue, Gottesman, and Rao (1983; Am J Hum Genet 35:1161-1178) calculated risk estimates of 12.8% for offspring and 3.5… (More)

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Cite this paper

@article{MylesWorsley2007RecurrenceRT, title={Recurrence risk to offspring in extended multiplex schizophrenia pedigrees from a Pacific Island isolate.}, author={Marina Myles-Worsley and Josepha Tiobech and Francisca Blailes and Victor Manabu Yano and Stephen V Faraone}, journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics}, year={2007}, volume={144B 1}, pages={41-4} }