Recurrence of reversible cerebral vasoconstriction syndrome
@article{Chen2015RecurrenceOR,
title={Recurrence of reversible cerebral vasoconstriction syndrome},
author={Shih-Pin Chen and Jong-Ling Fuh and Jiing-Feng Lirng and Yen-Feng Wang and Shuu-Jiun Wang},
journal={Neurology},
year={2015},
volume={84},
pages={1552 - 1558}
}OBJECTIVE
We aimed to investigate whether reversible cerebral vasoconstriction syndrome (RCVS) could recur and to identify the potential predictors of recurrence in a large cohort of patients. [] Key Method All patients were regularly followed up by telephone after remission for RCVS and were particularly asked to return to our hospital immediately if they developed new acute, severe (i.e., thunderclap-like) headaches.
60 Citations
Post-reversible cerebral vasoconstriction syndrome headache
- Medicine, PsychologyThe Journal of Headache and Pain
- 2021
Post-RCVS headache is common, affecting half of patients and being disabling in one-tenth of patients, and higher anxiety level and migraine history are risk factors.
Long-Term Outcomes After Reversible Cerebral Vasoconstriction Syndrome
- Medicine, PsychologyStroke
- 2019
Overall, long-term outcome after RCVS is excellent, and independent predictors of relapse were having a history of migraine and having exercise as a trigger for thunderclap headache during initial RCVS.
Reversible cerebral vasoconstriction syndrome (RCVS): an interesting case report
- MedicineThe Journal of Headache and Pain
- 2021
Often underdiagnosed, pheochromocytoma could be an important condition associated with RCVS and it is important for clinicians to bear this diagnosis in mind while dealing with similar cases of recurrent thunderclap headaches.
Primary angiitis of the CNS and reversible cerebral vasoconstriction syndrome
- Medicine, PsychologyNeurology
- 2018
This study confirms that careful analysis of clinical context, headache features, and patterns of brain lesions can distinguish PACNS and RCVS within the first few days of admission in most cases.
Narrative Review: Headaches After Reversible Cerebral Vasoconstriction Syndrome
- Medicine, PsychologyCurrent Pain and Headache Reports
- 2020
Recurrence of thunderclap headaches or chronic headaches after RCVS is common in RCVS patients after the resolution of acute bouts, and several retrospective studies and case reports reported that chronic headaches are common.
Thunderclap headache and reversible cerebral vasoconstriction syndrome: Current theory and accumulated data
- Medicine, BiologyNeurology and Clinical Neuroscience
- 2019
Although prescription of triptans for migraine is not suitable for patients with a history of RCVS, lasmiditan, a highly selective 5‐HT1F receptor agonist, may be suitable in such cases, with prescription of bed rest, analgesics, and the removal of precipitating factors.
Current Treatment Options in Cardiovascular Medicine: Update on Reversible Cerebral Vasoconstriction Syndrome
- MedicineCurrent Treatment Options in Cardiovascular Medicine
- 2020
RCVS can now be accurately diagnosed using clinical and imaging features available upon presentation, and the recently developed “RCVS2 score” enables accurate bedside diagnosis with up to 99% specificity and 90% sensitivity, obviating the need for invasive tests to exclude mimics or confirm the diagnosis.
Reversible Cerebral Vasoconstriction Syndrome: Recognition and Treatment
- Medicine, PsychologyCurrent Treatment Options in Neurology
- 2017
The cornerstone of RCVS management remains largely supportive with bed rest and analgesics and removal of precipitating factors and Invasive neurointerventional techniques should be reserved for severe deteriorating cases.
Glucocorticoid-associated worsening in reversible cerebral vasoconstriction syndrome
- Medicine, PsychologyNeurology
- 2017
Patients with RCVS at risk for worsening can be identified on basis of baseline features, and Iatrogenic factors such as glucocorticoid exposure may contribute to worsening.
Anesthetic Management of Reversible Cerebral Vasoconstriction Syndrome: A Case Report.
- MedicineJournal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
- 2017
References
SHOWING 1-10 OF 20 REFERENCES
The clinical and radiological spectrum of reversible cerebral vasoconstriction syndrome. A prospective series of 67 patients.
- Medicine, PsychologyBrain : a journal of neurology
- 2007
The data suggest that RCVS is more frequent than previously thought, is more often secondary particularly to vasoactive substances, and should be considered in patients with recurrent thunderclap headaches, cSAH or cryptogenic strokes with severe headaches.
Reversible cerebral vasoconstriction syndromes: analysis of 139 cases.
- MedicineArchives of neurology
- 2011
Patients with reversible cerebral vasoconstriction syndromes have a unique set of clinical imaging features, with no significant differences between subgroups, and the effects of empirical treatment with calcium channel blockers and glucocorticoids are investigated.
Reversible cerebral vasoconstriction syndrome and cervical artery dissection in 20 patients
- Medicine, PsychologyNeurology
- 2013
The results point to the need for a systematic study of both cervical and intracranial arteries in the 2 conditions, and to the association of RCVS and CeAD, which was found in 12% of patients withRCVS and 7% of the authors' patients with CeAD.
Hemorrhagic Manifestations of Reversible Cerebral Vasoconstriction Syndrome: Frequency, Features, and Risk Factors
- Medicine, PsychologyStroke
- 2010
Overall, intracranial hemorrhages are frequent in RCVS and are associated with a more severe clinical spectrum and women and migrainers seem to be at higher risk of intrac Cranial hemorrhage.
Reversible cerebral vasoconstriction syndrome: an under-recognized clinical emergency
- MedicineTherapeutic advances in neurological disorders
- 2010
Most patients with RCVS recover without sequelae; however, relapse has been reported in a small proportion of patients, and calcium channel blockers, such as nimodipine may be an effective treatment in prevention of thunderclap headache attacks.
Autonomic dysfunction in reversible cerebral vasoconstriction syndromes
- Medicine, PsychologyThe Journal of Headache and Pain
- 2013
Decreased parasympathetic modulations and accentuated sympathetic activity might be a biological trait in patients with RCVS and improve partially but remained significantly different from controls during remission.
Narrative Review: Reversible Cerebral Vasoconstriction Syndromes
- MedicineAnnals of Internal Medicine
- 2007
This narrative review, by specialists in the field of rheumatology, headache, and stroke, will outline the cause and pathophysiology, symptoms and signs, diagnosis, treatment, and prognosis of RCVS and areas of uncertainty.
Recurrent primary thunderclap headache and benign CNS angiopathy
- MedicineNeurology
- 2006
This study suggests that the two diagnostic entities proposed by the ICHD-II may present different spectra of the same disorder, and may help physicians quickly recognize this disabling headache disorder with risk of stroke and provide timely treatment.
Oxidative stress and increased formation of vasoconstricting F2-isoprostanes in patients with reversible cerebral vasoconstriction syndrome.
- MedicineFree radical biology & medicine
- 2013
Benign angiopathy of the central nervous system: cohort of 16 patients with clinical course and long-term followup.
- Medicine, PsychologyArthritis and rheumatism
- 2002
There is a PACNS subset characterized by acute presentation, normal to mildly abnormal CSF findings, female predominance, and highly abnormal cerebral angiography (reversible after treatment), requiring less intensive treatment than has been traditionally used.



