Recurrence of Respiratory Depression Following Neurolept Analgesia

@article{Nilsson1982RecurrenceOR,
  title={Recurrence of Respiratory Depression Following Neurolept Analgesia},
  author={C. Nilsson and B. Rosberg},
  journal={Acta Anaesthesiologica Scandinavica},
  year={1982},
  volume={26}
}
Fentanyl, though generally regarded as a short‐acting narcotic analgesic, can give unexpected respiratory depression several hours after the last dose. This potentially very dangerous effect is explained in pharmacokinetic studies by a mobilisation of fentanyl from tissue stores. In this report we describe a patient who, following a Harrington correction for scoliosis done with neurolept analgesia, developed a severe respiratory depression 5 h after the last dose of fentanyl. 

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