Rectal propranolol controls paroxysmal sympathetic hyperactivity: a case report.

@article{May2015RectalPC,
  title={Rectal propranolol controls paroxysmal sympathetic hyperactivity: a case report.},
  author={Casey C May and Douglas R Oyler and Sara E Parli and Cynthia L Talley},
  journal={Pharmacotherapy},
  year={2015},
  volume={35 4},
  pages={e27-31}
}
Paroxysmal sympathetic hyperactivity (PSH) affects approximately 10% of survivors of acquired brain injury and is associated with substantial morbidity. The most effective maintenance therapies include oral β-blockers and α-2 antagonists. We report the use of rectal propranolol for symptomatic control of PSH in a critically ill patient with an altered gastrointestinal tract for whom oral intake was contraindicated. A 15-year-old Caucasian male with no past medical history was admitted status… CONTINUE READING
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