Rectal Drug Administration

@article{Boer1982RectalDA,
  title={Rectal Drug Administration},
  author={A. Boer and F. Moolenaar and L. G. J. Leede and D. Breimer},
  journal={Clinical Pharmacokinetics},
  year={1982},
  volume={7},
  pages={285-311}
}
  • A. Boer, F. Moolenaar, +1 author D. Breimer
  • Published 1982
  • Medicine
  • Clinical Pharmacokinetics
  • SummaryThe human rectum represents a body cavity in which drugs can be easily introduced and retained and from which absorption is well possible. There are important therapeutic reasons why it is sometimes preferable to give a drug rectally rather than orally, e.g. in cases of nausea and vomiting. Drawbacks of rectal drug administration include the interruption of absorption by defaecation and lack of patient acceptability. The mechanism of drug absorption from the rectum is probably no… CONTINUE READING
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