Rectal Administration of Lactobacillus casei DG Modifies Flora Composition and Toll-Like Receptor Expression in Colonic Mucosa of Patients with Mild Ulcerative Colitis

@article{Dinc2010RectalAO,
  title={Rectal Administration of Lactobacillus casei DG Modifies Flora Composition and Toll-Like Receptor Expression in Colonic Mucosa of Patients with Mild Ulcerative Colitis},
  author={Renata D’inc{\`a} and Michela Barollo and Marco Scarpa and Alessia Rosaria Grillo and Paola Brun and Maria Grazia Vettorato and Ignazio Castagliuolo and Giacomo carlo Sturniolo},
  journal={Digestive Diseases and Sciences},
  year={2010},
  volume={56},
  pages={1178-1187}
}
An imbalance in gut microbiota seems to contribute to the development of chronic inflammatory disorders of the gastrointestinal tract, such as ulcerative colitis (UC). Although it has been suggested that probiotic supplementation is an effective approach to colitis, its effects on intestinal flora and on mucosal cytokine balance have never been explored. To evaluate the effect of Lactobacillus casei (L. casei) DG, a probiotic strain, on colonic-associated microbiota, mucosal cytokine balance… CONTINUE READING

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