Recruitment of Armitage and Yb to a transcript triggers its phased processing into primary piRNAs in Drosophila ovaries

@article{Pandey2017RecruitmentOA,
  title={Recruitment of Armitage and Yb to a transcript triggers its phased processing into primary piRNAs in Drosophila ovaries},
  author={R. R. Pandey and David Homolka and Kuan-Ming Chen and R. Sachidanandam and M. Fauvarque and R. Pillai},
  journal={PLoS Genetics},
  year={2017},
  volume={13}
}
Small RNAs called PIWI -interacting RNAs (piRNAs) are essential for transposon control and fertility in animals. Primary processing is the small RNA biogenesis pathway that uses long single-stranded RNA precursors to generate millions of individual piRNAs, but the molecular mechanisms that identify a transcript as a precursor are poorly understood. Here we demonstrate that artificial tethering of the piRNA biogenesis factor, Armi, to a transcript is sufficient to direct it into primary… Expand
Zucchini-dependent piRNA processing is triggered by recruitment to the cytoplasmic processing machinery.
piRNA Biogenesis in Drosophila melanogaster.
Ribosomes guide pachytene piRNA formation on long intergenic piRNA precursors
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References

SHOWING 1-10 OF 43 REFERENCES
...
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3
4
5
...