Recruitment and subsequent proliferation of bone marrow-derived cells in the postischemic kidney are important to the progression of fibrosis.

@article{Jang2014RecruitmentAS,
  title={Recruitment and subsequent proliferation of bone marrow-derived cells in the postischemic kidney are important to the progression of fibrosis.},
  author={Hee-Seong Jang and Jee In Kim and Sang Jun Han and Kwon Moo Park},
  journal={American journal of physiology. Renal physiology},
  year={2014},
  volume={306 12},
  pages={F1451-61}
}
Acute kidney injury (AKI) is an independent risk factor of the development of chronic kidney disease. Kidney fibrosis is a typical feature of chronic kidney disease and is characterized as an expansion of the interstitium due to increases in extracellular matrix molecules and interstitial cells caused by accumulations of extrarenal cells and by the proliferation or differentiation of intrarenal cells. However, the role of bone marrow-derived cells (BMDCs) in AKI-induced kidney fibrosis remains… CONTINUE READING
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