Recovery of the blood-aqueous barrier after topical chemical irritation in the rabbit eye

@article{Krootila1987RecoveryOT,
  title={Recovery of the blood-aqueous barrier after topical chemical irritation in the rabbit eye},
  author={Kari Krootila and H. Uusitalo and Juha I. Lehtosalo and Arto Palkama},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={1987},
  volume={225},
  pages={272-276}
}
An acute irritative response in the rabbit eye, taking the form of a rise in the intraocular pressure (IOP), miosis, and breakdown of the blood-aqueous barrier, was elicited by topical application of 1% neutral formaldehyde. The peak rise in IOP was 22.1 ± 2.5 mmHg and occurred within 14.2 ± 1.9 min, after which IOP returned to normal values in 45.4 ± 5.2 min. An increased amount of i.v.-injected Evans Blue was found in the aqueous humour when injected 15 min after the irritation (119.0 ± 21.2… CONTINUE READING

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1 Excerpt