Recovery of structurally intact and infectious poliovirus type 1 from HeLa cells during receptor-mediated endocytosis.

@article{Willingmann1989RecoveryOS,
  title={Recovery of structurally intact and infectious poliovirus type 1 from HeLa cells during receptor-mediated endocytosis.},
  author={P Willingmann and H. J. Barnert and Heinz Zeichhardt and Kathleen Habermehl},
  journal={Virology},
  year={1989},
  volume={168 2},
  pages={417-20}
}
Poliovirus type 1 enters HeLa cells by receptor-mediated endocytosis as an intact virus. Up to 30 min after adsorption complete virus particles still containing VP4 and sedimenting with 156 S could be recovered from the cells. These virus particles were N-antigenic and infectious. Thirty minutes after adsorption the recovery of intact and infectious virus… CONTINUE READING