Recovery of state-specific potential of molecular motor from single-molecule trajectory

@article{Toyabe2012RecoveryOS,
  title={Recovery of state-specific potential of molecular motor from single-molecule trajectory},
  author={Shoichi Toyabe and Hiroshi Ueno and Eiro Muneyuki},
  journal={EPL},
  year={2012},
  volume={97},
  pages={40004}
}
We have developed a novel method to evaluate the potential profile of a molecular motor at each chemical state from only the probe's trajectory and applied it to a rotary molecular motor F1-ATPase. By using this method, we could also obtain the information regarding the mechanochemical coupling and energetics. We demonstrate that the position-dependent transition of the chemical states is the key feature for the highly efficient free-energy transduction by F1-ATPase. 
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We describe the energetics of motor proteins by taking F\(_1\)-ATPase as an example. To clarify the meaning of the mechanical works which are experimentally measured, we first identify the heat,
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